Successful Treatment of Kodamaea ohmeri Bloodstream Infection with Voriconazole: A Case Report and Literature Review
<i>Kodamaea ohmeri</i> is an emerging opportunistic yeast pathogen frequently misidentified as <i>Candida</i>, posing significant diagnostic challenges. This report describes a case of <i>K. ohmeri</i> bloodstream infection in a 70-year-old female with poorly controlled diabetes following radical gastrectomy. Despite broad-spectrum antibacterial therapy for postoperative complications, she developed persistent fever. Blood cultures identified <i>K. ohmeri</i>, and antifungal susceptibility testing (AST) revealed a low voriconazole minimum inhibitory concentration (0.06 μg/mL), prompting targeted therapy that led to the clearance of fungemia and full clinical recovery. This case underscores the critical importance of rapid pathogen identification and AST-directed therapy in managing life-threatening <i>K. ohmeri</i> infections.
Authors
- Shengnan Pan (ORCID: https://orcid.org/0009-0004-9266-0635)
- Chaogui Tang (ORCID: https://orcid.org/0000-0002-4502-7261)
- Ning Lin (ORCID: https://orcid.org/0000-0001-9573-7811)
- Lijun Yao (ORCID: https://orcid.org/0000-0001-6131-8491)
- Lijing Guo (ORCID: https://orcid.org/0009-0000-3059-8099)
- K. T. Li (ORCID: https://orcid.org/0009-0007-7832-5162)
- L. Lan (ORCID: https://orcid.org/0000-0003-1075-9099)
- Weiren Zhu (ORCID: https://orcid.org/0000-0002-6568-738X)
- Weichen Huang
- Xuemin Jin (ORCID: https://orcid.org/0009-0003-2572-4785)
- Chang Li
- Qianhui Li (ORCID: https://orcid.org/0000-0002-1439-0957)
- Jingjing Huang (ORCID: https://orcid.org/0009-0007-5963-9991)
- Shuxin Sun (ORCID: https://orcid.org/0000-0002-9525-6142)
- Qibing Xiong (ORCID: https://orcid.org/0009-0001-6436-7739)
Institutions
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s564291
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing Medical University