Loop-Mediated Isothermal Amplification (LAMP) for Rapid and Sensitive Detection of Carbapenemase Genes in CRE: A Diagnostic Validation Study
LAMP technology shows high diagnostic accuracy for detecting major carbapenemase genes particularly KPC and NDM in CRE isolates, offering a reliable tool for guiding appropriate antibiotic therapy. Its operational simplicity and cost-effectiveness make it particularly suitable for implementation in primary healthcare settings.
Authors
- Tian-tian Gou (ORCID: https://orcid.org/0009-0001-5541-1953)
- Ya‐Chen Liang (ORCID: https://orcid.org/0000-0001-7813-8921)
- Ling Li (ORCID: https://orcid.org/0000-0003-2371-6215)
Institutions
- Fourth People's Hospital of Sichuan Province (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s559992
- Primary Topic
- Biosensors and Analytical Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00