Impact of implementing a thromboelastometry-guided transfusion strategy on fibrinogen supplementation and transfusion in women with postpartum hemorrhage

Implementing a thromboelastometry-guided protocol was associated with significantly reduced use of fibrinogen concentrate, red blood cells, fresh frozen plasma, and platelet concentrates, without increasing the risk of progression to massive hemorrhage. Further assessments of maternal outcomes and cost-effectiveness are required.

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Publication Details

Journal
Journal of Clinical Anesthesia
Published
2025-12-12
DOI
https://doi.org/10.1016/j.jclinane.2025.112102
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
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article

Impact of implementing a thromboelastometry-guided transfusion strategy on fibrinogen supplementation and transfusion in women with postpartum hemorrhage

Aihua Zheng, Christophe Nougier, Lionel Bouvet, François‐Pierrick Desgranges et al.
Journal of Clinical Anesthesia
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Impact of implementing a thromboelastometry-guided transfusion strategy on fibrinogen supplementation and transfusion in women with postpartum hemorrhage

Aihua Zheng, Christophe Nougier, Lionel Bouvet, François‐Pierrick Desgranges, V. Chamouard, Charles‐Hervé Vacheron
article en

Abstract

Implementing a thromboelastometry-guided protocol was associated with significantly reduced use of fibrinogen concentrate, red blood cells, fresh frozen plasma, and platelet concentrates, without increasing the risk of progression to massive hemorrhage. Further assessments of maternal outcomes and cost-effectiveness are required.

Journal of Clinical AnesthesiaVol. 109
Université Claude Bernard Lyon 1 (FR), Hôpital Femme Mère Enfant (FR), Hospices Civils de Lyon (FR), Hôpital Lyon Sud (FR), Hôpital Nord (FR)
Openalex Percentile: Top 51%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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