Responses to active stand test predict 12-year incident cardiovascular disease and mortality
We observe distinct relationships between HR/BP responses to AS and 12-year incident CVD and mortality. BP recovery and CVD are also associated in an independent clinical validation cohort. Integrating the entire haemodynamic response may reveal more nuanced relationships between HR/BP responses to AS, CVD and mortality - serving as an integrative marker of neuro-cardiovascular health in midlife and beyond.
Authors
- Cathal McCrory (ORCID: https://orcid.org/0000-0001-6575-2367)
- Rose Anne Kenny (ORCID: https://orcid.org/0000-0002-9336-8124)
- Louise Newman (ORCID: https://orcid.org/0000-0001-8192-0447)
- Belinda Hernández (ORCID: https://orcid.org/0000-0001-5034-1282)
- Adam H. Dyer (ORCID: https://orcid.org/0000-0003-1356-510X)
- M.D. Ward (ORCID: https://orcid.org/0000-0001-6309-4866)
- Ciarán Finucane
Institutions
- Trinity College Dublin (IE)
- Tallaght University Hospital (IE)
- National Centre for Pharmacoeconomics (IE)
- St. James's Hospital (IE)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1038/s43856-025-01253-3
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science Foundation Ireland
- National Institute on Aging