Fecal microbiota transplantation to reduce immune activation in ART-treated people with HIV with low CD4/CD8 ratio: protocol for the single-blind, randomized, placebo-controlled Gutsy study (CIHR/CTN PT038)

Authors

Péter L. Lakatos (ORCID: https://orcid.org/0000-0002-3948-6488)
Carolina Berini
Léna Royston (ORCID: https://orcid.org/0000-0003-2367-7682)
Michael Silverman (ORCID: https://orcid.org/0000-0002-0389-7656)
Seema Nair Parvathy (ORCID: https://orcid.org/0000-0001-6738-000X)
Tsoarello Mabanga
Marina B. Klein (ORCID: https://orcid.org/0000-0002-3063-8430)
Talat Bessissow (ORCID: https://orcid.org/0000-0003-2610-1910)
Bertrand Lebouché (ORCID: https://orcid.org/0000-0002-1273-9393)
Stéphane Isnard (ORCID: https://orcid.org/0000-0001-6249-1659)
Jean‐Pierre Routy (ORCID: https://orcid.org/0000-0001-9897-7589)
Cecilia T. Costiniuk (ORCID: https://orcid.org/0000-0002-4547-714X)
Bertrand Routy (ORCID: https://orcid.org/0000-0003-1955-9149)
Hao Feng (ORCID: https://orcid.org/0009-0008-4099-4886)
Orthy Aiyana

Institutions

Western University (CA)
Lawson Health Research Institute (CA)
McGill University Health Centre (CA)
University Hospital of Geneva (CH)
Centre Hospitalier de l’Université de Montréal (CA)
St Joseph's Health Care (CA)
HIV Legal Network (CA)

Publication Details

Journal: Trials
Published: 2025-12-13
DOI: https://doi.org/10.1186/s13063-025-09345-0
Primary Topic: Clostridium difficile and Clostridium perfringens research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Fecal microbiota transplantation to reduce immune activation in ART-treated people with HIV with low CD4/CD8 ratio: protocol for the single-blind, randomized, placebo-controlled Gutsy study (CIHR/CTN PT038)

Péter L. Lakatos, Carolina Berini, Léna Royston, Michael Silverman et al.

Dec 13, 2025

Trials

Clostridium difficile and Clostridium perfringens research

article

Fecal microbiota transplantation to reduce immune activation in ART-treated people with HIV with low CD4/CD8 ratio: protocol for the single-blind, randomized, placebo-controlled Gutsy study (CIHR/CTN PT038)

Péter L. Lakatos, Carolina Berini, Léna Royston, Michael Silverman, Seema Nair Parvathy, Tsoarello Mabanga, Marina B. Klein, Talat Bessissow, Bertrand Lebouché, Stéphane Isnard, Jean‐Pierre Routy, Cecilia T. Costiniuk, Bertrand Routy, Hao Feng, Orthy Aiyana

December 13, 2025article en

Abstract

No abstract available for this paper.

TrialsVol. 27(1)

Western University (CA), Lawson Health Research Institute (CA), McGill University Health Centre (CA), University Hospital of Geneva (CH), Centre Hospitalier de l’Université de Montréal (CA), St Joseph's Health Care (CA), HIV Legal Network (CA)

Openalex Percentile: Top 53%

Clostridium difficile and Clostridium perfringens research

DOI Open Access PDF OpenAlex

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