A new member of the novel, non-core Brucella clade: An exotic frog isolate closely related to atypical Brucella isolates from recent human brucellosis cases in Australia
In summary, the amphibian-derived strain Brucella sp. CVUAS_1139.3 clusters phylogenetically with and is phenotypically alike to previously reported isolates from amphibian hosts and human brucellosis patients within the novel, non-core clade. Our report and other studies suggest that exotic frogs are potential reservoirs for human pathogenic Brucella spp., which might pose an underestimated zoonotic hazard for exposed individuals.
Authors
- Dirk Hofreuter (ORCID: https://orcid.org/0000-0002-2589-9206)
- Franck Cantet (ORCID: https://orcid.org/0000-0001-6634-8331)
- Stephan Köhler (ORCID: https://orcid.org/0000-0002-3857-3088)
- Christoph-Martin Ufermann (ORCID: https://orcid.org/0000-0002-4779-5424)
- Boyke Bunk (ORCID: https://orcid.org/0000-0002-8420-8161)
- Rainer Oehme
- Cathrin Spröer
- Ashish K. Gadicherla (ORCID: https://orcid.org/0000-0001-7013-4264)
- Sascha Al Dahouk (ORCID: https://orcid.org/0000-0003-3835-0818)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Montpellier (FR)
- Medical College of Wisconsin (US)
- Robert Koch Institute (DE)
- Federal Institute for Risk Assessment (DE)
- Institut de Recherche en Infectiologie de Montpellier (FR)
- Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures (DE)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1186/s12866-025-04479-2
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00