Synovial Fluid Autoantibodies and Cytokines in Rheumatoid Arthritis Potential Biomarkers and Insight into Disease Pathogenesis
We identified three new autoantibodies and a new cytokine in RA SF. These findings, along with our enrichment analysis, suggest a potential role for NETs in the RA synovial microenvironment. This deepens our understanding of RA synovial microenvironment and identifies new approaches for innovative treatment strategies.
Authors
- Yanli Xie (ORCID: https://orcid.org/0000-0002-3895-5959)
- Shiyao Wu (ORCID: https://orcid.org/0000-0003-2843-2772)
- Ying Jiang (ORCID: https://orcid.org/0000-0002-4809-0258)
- Xiaoli Zhang
- Quan‐Zhen Li (ORCID: https://orcid.org/0000-0002-7257-0489)
- Li Wang (ORCID: https://orcid.org/0000-0001-5987-2266)
- Hong–Lin Zhu (ORCID: https://orcid.org/0000-0002-0989-7016)
- Tong Li (ORCID: https://orcid.org/0000-0003-3725-1420)
- Xiaoxia Zuo
- Jiaomei Cheng
- Yaou Zhou
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Archives of Medical Research
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.arcmed.2025.103329
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00