From urinary tract infection to deafness: community-acquired meningitis in an adult caused by hypervirulent Klebsiella pneumoniae—a case report
This case highlights the urinary tract as an underrecognized but lethal source of hvKP dissemination, particularly in diabetic patients. The rapid neurologic decline and permanent deafness highlight the need for early recognition and aggressive management. Virulence gene profiling should complement routine susceptibility testing. mNGS enabled rapid pathogen identification and guided targeted therapy. Clinicians must remain vigilant for CNS complications in diabetic patients with CA-UTI.
Authors
- Xiaohui Yuan (ORCID: https://orcid.org/0000-0002-2082-2146)
- Xingqiang Zhou
- Tao Wang (ORCID: https://orcid.org/0000-0001-6286-0119)
- Min Fang (ORCID: https://orcid.org/0000-0001-5241-6460)
- Simin Yang (ORCID: https://orcid.org/0000-0001-9362-2789)
- Lan Wei (ORCID: https://orcid.org/0000-0002-4302-0613)
Institutions
- Huizhou Central People's Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1186/s12879-025-12340-0
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00