From urinary tract infection to deafness: community-acquired meningitis in an adult caused by hypervirulent Klebsiella pneumoniae—a case report

This case highlights the urinary tract as an underrecognized but lethal source of hvKP dissemination, particularly in diabetic patients. The rapid neurologic decline and permanent deafness highlight the need for early recognition and aggressive management. Virulence gene profiling should complement routine susceptibility testing. mNGS enabled rapid pathogen identification and guided targeted therapy. Clinicians must remain vigilant for CNS complications in diabetic patients with CA-UTI.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-12-13
DOI
https://doi.org/10.1186/s12879-025-12340-0
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

From urinary tract infection to deafness: community-acquired meningitis in an adult caused by hypervirulent Klebsiella pneumoniae—a case report

Xiaohui Yuan, Xingqiang Zhou, Tao Wang, Min Fang et al.
BMC Infectious Diseases
Bacterial Infections and Vaccines
article

From urinary tract infection to deafness: community-acquired meningitis in an adult caused by hypervirulent Klebsiella pneumoniae—a case report

Xiaohui Yuan, Xingqiang Zhou, Tao Wang, Min Fang, Simin Yang, Lan Wei
article en

Abstract

This case highlights the urinary tract as an underrecognized but lethal source of hvKP dissemination, particularly in diabetic patients. The rapid neurologic decline and permanent deafness highlight the need for early recognition and aggressive management. Virulence gene profiling should complement routine susceptibility testing. mNGS enabled rapid pathogen identification and guided targeted therapy. Clinicians must remain vigilant for CNS complications in diabetic patients with CA-UTI.

BMC Infectious DiseasesVol. 26(1)
Huizhou Central People's Hospital (CN)
Openalex Percentile: Top 61%
Bacterial Infections and Vaccines
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