Integrative Genomic and Single‐Cell Insights Into Efferocytosis‐Mediated Immune Regulation in Clear Cell Renal Cell Carcinoma
Efferocytosis activation characterizes aggressive ccRCC. The developed prognostic model and identification of RAC1 as a central effector link efferocytosis-related risk to immune remodeling and oncogenic signaling, providing potential biomarkers and therapeutic targets.
Authors
- Mingcong Zhang (ORCID: https://orcid.org/0009-0000-4093-9731)
- Minghao Deng
- Zhenhua Jin
- Anli Zhu
- Jiakang Ma (ORCID: https://orcid.org/0000-0002-3327-0600)
- Shuijie Shen (ORCID: https://orcid.org/0000-0002-3018-8142)
- Jian Zhu (ORCID: https://orcid.org/0000-0002-3147-4319)
- Chao Chen (ORCID: https://orcid.org/0009-0004-8483-3743)
- Rongchao Yang
- Aijin Peng
- Bing Zhi Shi (ORCID: https://orcid.org/0009-0000-2664-294X)
Institutions
- Henan University of Science and Technology (CN)
- Ningbo No. 2 Hospital (CN)
- The First People’s Hospital of Lianyungang (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Ningbo University Affiliated Hospital (CN)
- Anyang Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Mediators of Inflammation
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/mi/8710699
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical and Health Research Project of Zhejiang Province