Development of an electrochemiluminescence assay to measure serum darbepoetin concentration in extremely preterm infants
A reliable and accurate assay to measure Darbe concentrations in serum or plasma was developed and validated on a clinically translatable platform. This method will be applied to quantify Darbe serum concentrations in extremely premature infants and to perform population pharmacokinetic analyses.<b>Clinical Trial Registration:</b> https://clinicaltrials.gov/study/NCT03169881. Identifier is NCT03169881.
Authors
- D. C. Winter (ORCID: https://orcid.org/0000-0002-9559-6438)
- Lauren L. Jantzie (ORCID: https://orcid.org/0000-0002-5410-3553)
- Robin K. Ohls (ORCID: https://orcid.org/0000-0003-2865-8878)
- Guohua An (ORCID: https://orcid.org/0000-0002-6498-7663)
- Sandra Sundquist Beauman
- Jessie R. Maxwell (ORCID: https://orcid.org/0000-0001-8990-7239)
- Jonathan Buhrman
Institutions
- University of Iowa (US)
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- University of New Mexico (US)
- University of Utah (US)
- Johns Hopkins Medicine (US)
- University of California System (US)
- University of California San Diego (US)
- Meso Scale Discovery (United States) (US)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1080/17576180.2025.2600914
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00