Hyperthermia upregulates exosomal miR-210-3p to target <i>GPD1L</i> activating PI3K/AKT pathway and promoting atrial fibrosis
These findings underscore the crucial role of miR-210-3p in exosomes derived from cardiomyocytes in atrial fibrosis following IRFA through <i>GPD1L</i>, providing new potential targets and mechanisms for the treatment of AF-related fibrosis.
Authors
- Zhongbao Ruan (ORCID: https://orcid.org/0000-0003-0607-0010)
- Feixing Li (ORCID: https://orcid.org/0000-0003-1851-0730)
- Huixian Li (ORCID: https://orcid.org/0000-0002-3340-9481)
Institutions
- Hebei North University (CN)
- Dalian Medical University (CN)
- Nantong University (CN)
- Taizhou Fourth People's Hospital (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- International Journal of Hyperthermia
- Published
- 2025-12-14
- DOI
- https://doi.org/10.1080/02656736.2025.2583160
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00