Stimulation of High‐Conductivity Points in Human Skin Reduces Biotin Levels to Modulate Intracellular Metabolism and Local Energy Production
These findings suggest that biotin-dependent metabolic reprogramming occurs at electrically distinct skin regions in response to physical stimulation. While the relationship between HCPs and classical acupoints remains to be fully established, this study provides novel insights into the local biochemical responses associated with acupuncture.
Authors
- Kazuki Takagaki (ORCID: https://orcid.org/0000-0002-8153-8077)
- Andrea Clocchiatti (ORCID: https://orcid.org/0000-0003-4339-2553)
- Kentaro Kajiya (ORCID: https://orcid.org/0000-0002-5224-7051)
- Stefano Sol (ORCID: https://orcid.org/0000-0003-2576-0156)
- Anna Mandinova (ORCID: https://orcid.org/0000-0001-9273-0972)
- Fabiana Boncimino (ORCID: https://orcid.org/0009-0002-9409-7757)
- Kristina Todorova
Institutions
- Broad Institute (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Shiseido Group (Japan) (JP)
- Mirai Hospital (JP)
- Harvard Stem Cell Institute (US)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/hsr2.71512
- Primary Topic
- Biotin and Related Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Harvard T.H. Chan School of Public Health