<scp>MRI</scp> of Neurogenic Human Motor Units Following Poliomyelitis
Polio survivors demonstrate motor units with normal dimensions but increased shape complexity, indicating nonuniform collateral reinnervation largely limited to existing territories. The size and shape of motor units could help in understanding the physiological processes behind reinnervation, both in polio and other neurogenic diseases such as amyotrophic lateral sclerosis.
Authors
- Stuart Maitland (ORCID: https://orcid.org/0000-0001-7879-016X)
- Matthew Birkbeck (ORCID: https://orcid.org/0000-0001-6041-8052)
- Ian Schofield (ORCID: https://orcid.org/0000-0002-1532-5049)
- Lawrence MJ Best (ORCID: https://orcid.org/0000-0003-1923-0896)
- Roger G. Whittaker (ORCID: https://orcid.org/0000-0002-3403-0182)
- Andrew M. Blamire (ORCID: https://orcid.org/0000-0002-8749-1257)
- James Scott
Institutions
- Cumbria Northumberland Tyne and Wear NHS Foundation Trust (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Freeman Hospital (GB)
- NIHR Newcastle Biomedical Research Centre (GB)
- Newcastle University (GB)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2025-12-14
- DOI
- https://doi.org/10.1002/mus.70107
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- Newcastle University
- NIHR Newcastle Biomedical Research Centre