Adjunctive phenobarbital for severe alcohol withdrawal
Most patients with alcohol withdrawal symptoms improve with benzodiazepines; however, certain individuals with severe withdrawal and functional γ-aminobutyric acid deficiency experience a blunted response. Benzodiazepine-resistant withdrawal is characterized by persistent or worsening symptoms (e.g
Authors
- Wiplove Lamba
- Danielle Buell
- Brady Bouchard (ORCID: https://orcid.org/0000-0003-3014-9212)
- Sarah Whynot
Institutions
- Mount Sinai Hospital (CA)
- Saskatchewan Hospital (CA)
- St Michael’s Hospital (IE)
- St Joseph's Health Centre (CA)
Publication Details
- Journal
- Canadian Medical Association Journal
- Published
- 2025-12-14
- DOI
- https://doi.org/10.1503/cmaj.250637
- Primary Topic
- Alcoholism and Thiamine Deficiency
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Toronto