Prostogrit mitigates testosterone/estradiol induced prostatic enlargement/remodeling in rat model of benign prostatic hyperplasia and fine-tunes prostatic expression of Adra1a and Il6 genes
The findings of the current proof of concept study suggest that Prostogrit has pharmacological effects in an animal model of BPH. Accordingly, it possesses preclinical potential for the pharmacotherapeutic management of BPH, which merits further investigations.
Authors
- Rishabh Dev (ORCID: https://orcid.org/0000-0002-7878-6934)
- Rani Singh (ORCID: https://orcid.org/0000-0002-5819-4050)
- Meenu Tomer
- Anurag Varshney (ORCID: https://orcid.org/0000-0001-8509-0882)
- Acharya Balkrishna (ORCID: https://orcid.org/0000-0003-4749-6317)
- Venu Pamidiboina
- Sandeep Sinha (ORCID: https://orcid.org/0000-0003-1326-3769)
Institutions
- Patanjali Research Foundation (IN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-15
- DOI
- https://doi.org/10.3389/fendo.2025.1663917
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00