Use of oXiris® hemoadsorption in sepsis and acute kidney injury: a retrospective cohort study in a resource-limited Colombian ICU

In a resource-limited ICU, oXiris^®-based CRRT was associated with rapid vasopressor de-escalation and clinically meaningful kidney recovery among survivors, but overall mortality remained high and severity-dependent. COVID-19 septic shock showed a distinct profile, with higher baseline severity, a trend toward higher mortality, and impaired renal recovery. These data support feasibility and safety of hemoadsorptive CRRT in constrained settings and justify prospective comparative evaluation.