Adult‐Onset Still's Disease Complicated by Secondary Hemophagocytic Lymphohistiocytosis: A Case Report
Adult-onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by fever, rash, joint pain, and elevated ferritin levels. Systemic inflammation can trigger an exaggerated immune response, leading to secondary hemophagocytic lymphohistiocytosis (HLH). This case discusses AOSD complicated by HLH in a 29-year-old female, emphasizing prompt recognition and management.
Authors
- Georgia Kaiafa (ORCID: https://orcid.org/0000-0001-8000-4500)
- Eleftheria Ztriva (ORCID: https://orcid.org/0000-0002-4013-2767)
- Vasileios Patriarcheas (ORCID: https://orcid.org/0000-0001-6561-321X)
- Stavroula Bountola
- Christos Savopoulos (ORCID: https://orcid.org/0000-0002-7970-2464)
- Theodoros Dimitroulas (ORCID: https://orcid.org/0000-0002-0364-1642)
- Michail Makris
- Vasiliki Gougoula
- Athanasios Penopoulos
Institutions
- Aristotle University of Thessaloniki (GR)
- AHEPA University Hospital (GR)
- Ippokrateio General Hospital of Thessaloniki (GR)
- Hippocration General Hospital (GR)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/ccr3.71650
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00