Real-world retrospective study on the efficacy and safety of anti-IgE therapy combined with rush immunotherapy in allergic asthma

Regarding the safety of dust mite rush immunotherapy for allergic asthma, Omalizumab significantly reduces the incidence of SRs in high-risk populations (sIgE grades 3-6 and sIgE/T-IgE ≥10%), whereas it demonstrates limited efficacy in low-risk subgroups (sIgE grades 1-2 and sIgE/T-IgE <10%).

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Publication Details

Journal
Frontiers in Allergy
Published
2025-12-15
DOI
https://doi.org/10.3389/falgy.2025.1717446
Primary Topic
Allergic Rhinitis and Sensitization
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world retrospective study on the efficacy and safety of anti-IgE therapy combined with rush immunotherapy in allergic asthma

Zhao‐Ji Meng, Siqin Wang, Yinzi Jin, Dan Liu et al.
Frontiers in Allergy
Allergic Rhinitis and Sensitization
article

Real-world retrospective study on the efficacy and safety of anti-IgE therapy combined with rush immunotherapy in allergic asthma

Zhao‐Ji Meng, Siqin Wang, Yinzi Jin, Dan Liu, Wenchao Zhang, Xianghua Lin, Wenjin Du, Wei-Li Guo, Qiuxing Zhang
article en

Abstract

Regarding the safety of dust mite rush immunotherapy for allergic asthma, Omalizumab significantly reduces the incidence of SRs in high-risk populations (sIgE grades 3-6 and sIgE/T-IgE ≥10%), whereas it demonstrates limited efficacy in low-risk subgroups (sIgE grades 1-2 and sIgE/T-IgE <10%).

Frontiers in AllergyVol. 6
Henan Provincial People's Hospital (CN)
Openalex Percentile: Top 48%
Allergic Rhinitis and Sensitization
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