Unraveling the interaction between the phageome and bacteriome in the rumen and its role in influencing metabolome dynamics in dairy cows at different lactation stages

This study revealed the bacteriome and phageome interactions at different lactation stages, and the key phages and bacteria regulating the rumen function and metabolism thus contributing to the milk traits of cows. The potential regulatory roles of phages in affecting the rumen bacteriome suggest that they can be powerful targets for future interventions to improve rumen functions. Video Abstract.

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Publication Details

Journal
Microbiome
Published
2025-12-15
DOI
https://doi.org/10.1186/s40168-025-02260-1
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
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article

Unraveling the interaction between the phageome and bacteriome in the rumen and its role in influencing metabolome dynamics in dairy cows at different lactation stages

Zhijie Cui, Qingyan Yin, Yangchun Cao, Shengru Wu et al.
Microbiome
Bacteriophages and microbial interactions
article

Unraveling the interaction between the phageome and bacteriome in the rumen and its role in influencing metabolome dynamics in dairy cows at different lactation stages

Zhijie Cui, Qingyan Yin, Yangchun Cao, Shengru Wu, Xiaodong Chen, Mengya Wang, Junhu Yao, Jianrong Ren, Lichao Zhao, Yue Wang, Chenguang Zhang
article en

Abstract

This study revealed the bacteriome and phageome interactions at different lactation stages, and the key phages and bacteria regulating the rumen function and metabolism thus contributing to the milk traits of cows. The potential regulatory roles of phages in affecting the rumen bacteriome suggest that they can be powerful targets for future interventions to improve rumen functions. Video Abstract.

MicrobiomeVol. 13(1)
Inner Mongolia Agricultural University (CN), University of British Columbia (CA), North West Agriculture and Forestry University (CN), Northwest A&F University (CN)
Openalex Percentile: Top 61%
Bacteriophages and microbial interactions
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