Early Walnut Powder Introduction for Prevention of Walnut Sensitisation in High‐Risk Infants With Eczema: An Open‐Label, Randomised, Non‐Inferiority Trial
Summary Early walnut powder introduction in high‐risk infants may suppress walnut sensitisation without safety concerns. This randomised non‐inferiority trial compares introduction at 6–8 months versus 12–14 months of age.
Authors
- Seiko Hirai (ORCID: https://orcid.org/0000-0001-9359-6613)
- Sayaka Hamaguchi (ORCID: https://orcid.org/0009-0002-4885-5991)
- Yukihiro Ohya (ORCID: https://orcid.org/0000-0002-1560-3942)
- Kiwako Yamamoto‐Hanada (ORCID: https://orcid.org/0000-0003-1288-9620)
- Kenji Toyokuni (ORCID: https://orcid.org/0009-0002-2333-1817)
- Osamu Natsume (ORCID: https://orcid.org/0000-0002-6892-6219)
- Chikako Motomura (ORCID: https://orcid.org/0000-0001-9199-1302)
- Daisuke Harama (ORCID: https://orcid.org/0000-0002-2967-6739)
- Fumiya Yamaide (ORCID: https://orcid.org/0000-0002-2916-9710)
- Tomoki Yaguchi (ORCID: https://orcid.org/0000-0002-1903-6922)
- Hisako Ogasawara
- Tatsuki Fukuie (ORCID: https://orcid.org/0000-0003-4962-2137)
- Mami Shimada (ORCID: https://orcid.org/0009-0007-9188-5906)
- Mayako Saito‐Abe (ORCID: https://orcid.org/0000-0002-8845-7034)
- Kotaro Umezawa (ORCID: https://orcid.org/0009-0002-9099-6835)
- Daichi Suzuki (ORCID: https://orcid.org/0009-0002-5777-7497)
- Chisato Jimbo (ORCID: https://orcid.org/0009-0000-6317-1147)
Institutions
- Hamamatsu University (JP)
- Hamamatsu University School of Medicine (JP)
- Nagoya City University (JP)
- Fukuoka Hospital (JP)
- Nagoya City University Hospital (JP)
- Tokyo Metropolitan Hiroo Hospital (JP)
- National Center For Child Health and Development (JP)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1111/cea.70193
- Primary Topic
- Neonatal skin health care
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Center for Child Health and Development