The Effect of Psychotropic Medications on Glaucoma Risk and Intraocular Pressure: A Bayesian Meta-Analysis
While some drug classes (e.g., benzodiazepines, topiramate) show a strong association with glaucoma, results for other compounds must be taken judiciously. The high level of heterogeneity, and the presence of special populations suggest caution when moving to real-life scenarios. Nonetheless, our results highlight the importance of ophthalmologic monitoring in patients prescribed with psychiatric drugs (e.g., benzodiazepines or topiramate), at risk for angle closure.
Authors
- Cinzia Niolu (ORCID: https://orcid.org/0000-0001-6173-2684)
- Alberto Siracusano (ORCID: https://orcid.org/0000-0001-8406-093X)
- Tommaso B. Jannini (ORCID: https://orcid.org/0000-0003-2936-4150)
- Ludovico Alisi (ORCID: https://orcid.org/0000-0001-5366-882X)
- Francesca Giovannetti (ORCID: https://orcid.org/0000-0002-7661-6675)
- Marta Armentano (ORCID: https://orcid.org/0009-0005-3414-6344)
- Giorgio Di Lorenzo (ORCID: https://orcid.org/0000-0002-0576-4064)
Institutions
- University of Rome Tor Vergata (IT)
- Policlinico Umberto I (IT)
- Fondazione Santa Lucia (IT)
Publication Details
- Journal
- CNS Drugs
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1007/s40263-025-01249-6
- Citations
- 2
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- Sapienza Università di Roma