Targeting the LINC01272-FUS signal axis inhibits the migration and invasion of testicular germ cell tumors
We identified the LINC01272-FUS axis as a critical regulatory pathway in TGCTs progression, providing mechanistic insights for developing liquid biopsy biomarkers and RNA-targeted therapies.
Authors
- Jinhui Shu (ORCID: https://orcid.org/0000-0002-0052-4424)
- Jian Cao (ORCID: https://orcid.org/0000-0002-1272-6357)
- Zhizhong Liu (ORCID: https://orcid.org/0009-0008-2563-9691)
- Fang Zhu (ORCID: https://orcid.org/0000-0002-6032-2306)
- Hao Bo
- Zailong Qin (ORCID: https://orcid.org/0000-0001-7109-6693)
- Ziyi Chen (ORCID: https://orcid.org/0000-0003-2933-3274)
- Liqing Fan (ORCID: https://orcid.org/0000-0002-8289-7362)
- Xueheng Zhao (ORCID: https://orcid.org/0009-0001-1050-2579)
- Lei Xue (ORCID: https://orcid.org/0000-0003-4495-0414)
Institutions
- Central South University (CN)
- Hunan Normal University (CN)
- Reproductive & Genetic Hospital CITIC-Xiangya (CN)
- Hunan Cancer Hospital (CN)
- National Engineering Research Center of Human Stem Cells (CN)
- Guangxi Maternal and Child Health Hospital (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12935-025-04095-0
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00