Longitudinal Study of Plasma Metabolites During Menopause and Their Associations With Later Onset of Metabolic Syndrome
Longitudinal changes in charged metabolites occur across the menopausal transition, with specific metabolites such as glutamate possibly contributing to the metabolic alterations underlying increased MetS risk.
Authors
- Aya Hirata (ORCID: https://orcid.org/0000-0003-1439-4242)
- Daisuke Sugiyama (ORCID: https://orcid.org/0000-0002-6487-8934)
- Tomonori Okamura (ORCID: https://orcid.org/0000-0003-0488-0351)
- Masaru Tomita (ORCID: https://orcid.org/0000-0003-3423-377X)
- Wataru Yamagami (ORCID: https://orcid.org/0000-0003-3925-6057)
- Miho Iida (ORCID: https://orcid.org/0000-0001-5527-7574)
- Iori Kisu (ORCID: https://orcid.org/0000-0003-1143-9855)
- Tomoyoshi Soga (ORCID: https://orcid.org/0000-0001-9502-2509)
- Akiyoshi Hirayama (ORCID: https://orcid.org/0000-0002-0440-6820)
- Toru Takebayashi (ORCID: https://orcid.org/0000-0002-8268-8026)
- Sei Harada (ORCID: https://orcid.org/0000-0003-2666-4932)
- Naoko Miyagawa (ORCID: https://orcid.org/0000-0002-9148-1078)
- Kazuharu Arakawa (ORCID: https://orcid.org/0000-0002-2893-4919)
- Masahiro Sugimoto (ORCID: https://orcid.org/0000-0003-3316-2543)
- Asako Sato (ORCID: https://orcid.org/0009-0007-3057-1313)
- Minako Matsumoto (ORCID: https://orcid.org/0000-0002-7705-9903)
- Ryota Toki
- Shun Edagawa
- Atsuko Miyake (ORCID: https://orcid.org/0000-0003-1391-4576)
- Kaori Amano
- Kazuyo Kuwabara
Institutions
- Yamagata University (JP)
- Fujita Health University (JP)
- Bunkyo University (JP)
- Keio University (JP)
- Tokyo Metropolitan Institute of Public Health (JP)
- Keio University Hospital (JP)
- Keio University Shonan Fujisawa (JP)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1210/clinem/dgaf666
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science