In vitro anti-diabetic activity and molecular docking studies of Amaranthus cruentus, Amaranthus hybridus and isolated compounds

This study validates A. cruentus and A. hybridus's traditional use for the treatment of diabetes mellitus. Future studies will investigate the underlying mechanisms by which the extracts and compounds enhance glucose uptake in L6 myoblasts and C3A hepatocytes. Additionally, to provide a more comprehensive understanding of the antidiabetic potential of the Amaranthus extracts and compounds, in vivo experiments using appropriate animal models will be conducted.