Plasma pTau217 and Neurofilament Light Chain as Differentiative Markers for Progressive Supranuclear Palsy From Parkinson Disease

The combination of plasma pTau217 and NfL with brain MRI represents a noninvasive and clinically feasible strategy for distinguishing PSP from PD.

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Publication Details

Journal
Neurology
Published
2025-12-12
DOI
https://doi.org/10.1212/wnl.0000000000214406
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Plasma pTau217 and Neurofilament Light Chain as Differentiative Markers for Progressive Supranuclear Palsy From Parkinson Disease

Pin‐Shiuan Chen, Ing‐Tsung Hsiao, Min‐Yu Lan, Jung‐Lung Hsu et al.
Neurology
Parkinson's Disease Mechanisms and Treatments
article

Plasma pTau217 and Neurofilament Light Chain as Differentiative Markers for Progressive Supranuclear Palsy From Parkinson Disease

Pin‐Shiuan Chen, Ing‐Tsung Hsiao, Min‐Yu Lan, Jung‐Lung Hsu, Chin‐Hsien Lin, Yung‐Yee Chang, Hsiu-Chen Chang, Sung‐Pin Fan, Chun‐Yu Chen, Chiung-Chih Chang, Cheng‐Hsuan Li, Yih-Ru Wu, Chi-Wei Huang, Hung Chiang, Tsung-Lin Lee, Chin‐Song Lu
article en

Abstract

The combination of plasma pTau217 and NfL with brain MRI represents a noninvasive and clinically feasible strategy for distinguishing PSP from PD.

NeurologyVol. 106(1)
National Yang Ming Chiao Tung University (TW), National Taiwan University of Science and Technology (TW), National Taiwan University (TW), Chang Gung University (TW), Taipei Veterans General Hospital (TW), Chang Gung Memorial Hospital (TW), Landseed Hospital (TW), Kaohsiung Chang Gung Memorial Hospital (TW), Tao Yuan General Hospital (TW), Linkou Chang Gung Memorial Hospital (TW), National Taiwan University Hospital (TW), National Cheng Kung University Hospital (TW), Taipei Medical University (TW), National Cheng Kung University (TW)
Openalex Percentile: Top 45%
Parkinson's Disease Mechanisms and Treatments
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Plasma pTau217 and Neurofilament Light Chain as Differentiative Markers for Progressive Supranuclear Palsy From Parkinson Disease — Pin‐Shiuan Chen, Ing‐Tsung Hsiao, et al. · Neurology (2025) | TGRS Research Map | TGRS