Androgen‐Deprivation Therapy and Dietary Habits Influence the Gut Microbial Environment in Patients With High‐Risk Localized Prostate Cancer

Short-term ADT was found to increase the proportion of gut genus Ruminococcus 2 in patients with advanced prostate cancer, which was associated with low TS levels and showed a negative correlation with n-3 polyunsaturated fatty acid intake. Further validation is important to identify specific changes in the gut microbiota during ADT in patients with prostate cancer.

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Publication Details

Journal
The Prostate
Published
2025-12-13
DOI
https://doi.org/10.1002/pros.70109
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Androgen‐Deprivation Therapy and Dietary Habits Influence the Gut Microbial Environment in Patients With High‐Risk Localized Prostate Cancer

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Androgen‐Deprivation Therapy and Dietary Habits Influence the Gut Microbial Environment in Patients With High‐Risk Localized Prostate Cancer

Masanori Ishida, Tomonori Habuchi, Mizuki Kobayashi, Kazuyuki Numakura, Shinji Fukuda, Kazuki Funahashi, Shintaro Narita, Soki Kashima, Yohsuke Yamauchi, Ryohei Yamamoto, Yuya Sekine, Mitsuru Saito, Yoshiko Takahashi, Hiromi Sato
article en

Abstract

Short-term ADT was found to increase the proportion of gut genus Ruminococcus 2 in patients with advanced prostate cancer, which was associated with low TS levels and showed a negative correlation with n-3 polyunsaturated fatty acid intake. Further validation is important to identify specific changes in the gut microbiota during ADT in patients with prostate cancer.

The ProstateVol. 86(5)
University of Tsukuba (JP), Kanagawa Institute of Technology (JP), Akita University (JP), Keio University (JP), Juntendo University (JP), National Hospital Organization Mito Medical Center (JP), Tsukuba Medical Center Hospital (JP), Kanagawa Industrial Technology Center (JP), National Health Insurance Service (KR), National Institute of Technology, Tsuruoka College (JP)
Openalex Percentile: Top 63%
Gut microbiota and health
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