Targeting <scp>RNA</scp> Polymerase I Inhibits Ribosome Biogenesis to Block Liver Fibrosis Progression
Pol I-regulated ribosome biogenesis is significantly increased during HSCs activation and liver fibrosis progression. Pol I may serve as a potential target for the diagnosis and treatment of liver fibrosis.
Authors
- Yu Zhang (ORCID: https://orcid.org/0000-0002-1059-9788)
- Lixian Yi
- Fatma A. Abouelnazar (ORCID: https://orcid.org/0000-0002-1852-3032)
- Yongmin Yan (ORCID: https://orcid.org/0000-0002-1990-1170)
- Shihui Li (ORCID: https://orcid.org/0000-0002-0360-3582)
- Yanjin Wang (ORCID: https://orcid.org/0009-0005-1484-2537)
- Jing Zhou (ORCID: https://orcid.org/0000-0001-8384-0192)
- Wei Luo (ORCID: https://orcid.org/0000-0003-1818-3469)
Institutions
- Jiangsu University (CN)
- Xuzhou Medical College (CN)
- Suzhou Vocational Health College (CN)
- Changzhou University (CN)
Publication Details
- Journal
- Liver International
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1111/liv.70478
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00