Case of Congenital Tularemia with Neuroinvasive Disease, Utah, USA

We diagnosed neuroinvasive tularemia in a neonate in Utah who had culture-negative pleocytosis in cerebrospinal fluid, rim-enhancing lesions on brain magnetic resonance imaging, and blood microbial cell-free DNA Francisella tularensis detection. Maternal history, serologic testing, and Francisella sp. identified in the fallopian tube by immunohistochemistry and 16S rRNA gene PCR strongly support congenital infection.

Authors

Publication Details

Journal
Emerging infectious diseases
Published
2025-12-01
DOI
https://doi.org/10.3201/eid3112.250703
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.00
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article

Case of Congenital Tularemia with Neuroinvasive Disease, Utah, USA

Julian A. Villalba, Elizabeth D Knackstedt, Bert K. Lopansri, Jody L. Lin et al.
Emerging infectious diseases
Bacillus and Francisella bacterial research
article

Case of Congenital Tularemia with Neuroinvasive Disease, Utah, USA

Julian A. Villalba, Elizabeth D Knackstedt, Bert K. Lopansri, Jody L. Lin, Bryce Nelson, Krow Ampofo, Anne Jeannette Blaschke, Andrew T. Pavia, Julu Bhatnagar, Amara Finch, Elizabeth L Ryals, Benjamin Kalm
article en

Abstract

We diagnosed neuroinvasive tularemia in a neonate in Utah who had culture-negative pleocytosis in cerebrospinal fluid, rim-enhancing lesions on brain magnetic resonance imaging, and blood microbial cell-free DNA Francisella tularensis detection. Maternal history, serologic testing, and Francisella sp. identified in the fallopian tube by immunohistochemistry and 16S rRNA gene PCR strongly support congenital infection.

Emerging infectious diseasesVol. 31(12)
Openalex Percentile: Top 63%
Bacillus and Francisella bacterial research
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