Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study
An LATP biopsy has a higher mean cost, and no significant difference in mean QALYs, compared with a TRUS biopsy at 4 mo after the procedure. A time of 4 mo is too soon to reflect any impact from the 5.7% diagnostic uplift for LATP versus TRUS biopsy on the detection of intermediate-/high-grade prostate cancer seen in the TRANSLATE trial. A further analysis beyond this period is needed to fully interpret the cost-effectiveness results.
Authors
- Teresa Campbell
- Altan Omer
- Steve Tuck
- José Francisco Juárez López (ORCID: https://orcid.org/0000-0002-6498-2635)
- Tom Leslie (ORCID: https://orcid.org/0000-0002-4155-1840)
- Freddie C. Hamdy (ORCID: https://orcid.org/0000-0003-2627-2154)
- Alastair Lamb (ORCID: https://orcid.org/0000-0002-2968-7155)
- Jessica Scaife (ORCID: https://orcid.org/0000-0001-5661-7921)
- Filipa Landeiro (ORCID: https://orcid.org/0000-0003-2842-2195)
- Amy Taylor (ORCID: https://orcid.org/0000-0001-9811-330X)
- Derek J. Rosario (ORCID: https://orcid.org/0000-0002-9086-3592)
- Aimi Hewitt (ORCID: https://orcid.org/0000-0002-1575-1486)
- James W.F. Catto (ORCID: https://orcid.org/0000-0003-2787-8828)
- Mutie Raslan (ORCID: https://orcid.org/0000-0001-9937-6961)
- Jane Wolstenholme (ORCID: https://orcid.org/0000-0001-7493-1850)
- John Reynard
- Alexander Ooms (ORCID: https://orcid.org/0000-0003-1877-8323)
- Christopher Berridge (ORCID: https://orcid.org/0000-0002-7497-7338)
- Krishna Narahari (ORCID: https://orcid.org/0000-0003-0257-7033)
- Sashi S. Kommu (ORCID: https://orcid.org/0000-0003-4257-2157)
- Richard J. Bryant (ORCID: https://orcid.org/0000-0002-8330-9251)
- Ioana R. Marian (ORCID: https://orcid.org/0000-0002-0692-8112)
- Vicki S Barber (ORCID: https://orcid.org/0000-0001-9631-3666)
- Ben Eddy (ORCID: https://orcid.org/0000-0003-1279-8956)
- Matthew C. Little (ORCID: https://orcid.org/0000-0002-2680-5697)
- Hannah Wells
- Jessica Whitburn (ORCID: https://orcid.org/0000-0001-8320-7725)
- Clàudia Mercader (ORCID: https://orcid.org/0000-0002-5710-958X)
- Clare Verrill (ORCID: https://orcid.org/0000-0002-4905-8233)
- Ruth E. Macpherson (ORCID: https://orcid.org/0000-0003-2852-3359)
- Sukanya Ghosh
- Rob Gray
- Hide Yamamoto
- Daniel W. Good
- R. Williams
- Matthew Liew
- Daniel Chung
Institutions
- Cardiff and Vale University Health Board (GB)
- NHS Lothian (GB)
- Maidstone and Tunbridge Wells NHS Trust (GB)
- Western General Hospital (GB)
- University Hospital of Wales (GB)
- Churchill Hospital (GB)
- Buckinghamshire Healthcare NHS Trust (GB)
- University Hospital Coventry (GB)
- Maidstone Hospital (GB)
- Milton Keynes Hospital (GB)
- Nuffield Orthopaedic Centre (GB)
- Wrightington, Wigan and Leigh NHS Foundation Trust (GB)
- University Hospitals Coventry and Warwickshire NHS Trust (GB)
- East Kent Hospitals University NHS Foundation Trust (GB)
- University of Oxford (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Kent and Canterbury Hospital (GB)
- Prostate Cancer UK (GB)
- Milton Keynes Hospital NHS Foundation Trust (GB)
- Oxford BioMedica (United Kingdom) (GB)
- Oxford University Hospitals NHS Trust (GB)
Publication Details
- Journal
- European Urology Focus
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.euf.2025.11.007
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00