Protective Role of CBD Against Nicotine Pouch–Induced Seizure Aggravation and Alterations in Brain Glymphatic Biomarkers
Chronic nicotine pouch exposure promotes seizure susceptibility through converging neuroimmune and glymphatic disruptions. Inhaled CBD counteracts these effects, supporting its potential as a targeted therapeutic strategy for nicotine-associated neurological risk.
Authors
- Bidhan Bhandari (ORCID: https://orcid.org/0000-0002-4933-711X)
- Nancy L. Young (ORCID: https://orcid.org/0000-0002-1739-3299)
- Ahmed A. Elmarakby (ORCID: https://orcid.org/0000-0002-3065-4457)
- Évila Lopes Salles (ORCID: https://orcid.org/0000-0001-6956-7409)
- Mohammad Seyyedi (ORCID: https://orcid.org/0000-0002-3120-8459)
- Lei P. Wang
- Abdulhakeem Al-Hashim (ORCID: https://orcid.org/0000-0001-9610-4020)
- Babak Baban
- Sahar Emami Naeini (ORCID: https://orcid.org/0000-0003-2907-2414)
- Hannah M. Rogers
- Jack C. Yu
Institutions
- The Graduate Center, CUNY (US)
- Augusta University (US)
- Augusta University Health (US)
- Gobierno de Canarias (ES)
Publication Details
- Journal
- Nicotine & Tobacco Research
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1093/ntr/ntaf253
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00