Admixture Analysis of Age of Onset in Late-Life Major Depressive Disorder
In our sample, MDD was characterized by a trimodal age-of-onset distribution with cut-off ages of 33 and 47 years. However, age-of-onset was found to be associated with only few clinical and vulnerability characteristics. Possible overlap between de age-of-onset subtypes in later life may obscure differentiation between the characteristics.
Authors
- Idan M. Aderka (ORCID: https://orcid.org/0000-0002-4177-9925)
- Almar A. L. Kok (ORCID: https://orcid.org/0000-0001-6398-2484)
- Fatima M. Kabia (ORCID: https://orcid.org/0000-0001-6868-4144)
- J.M. Hegeman
- Nathaly Rius Ottenheim (ORCID: https://orcid.org/0000-0002-0721-7152)
- Didi Rhebergen (ORCID: https://orcid.org/0000-0002-3741-9767)
- Aartjan T.F. Beekman (ORCID: https://orcid.org/0000-0003-2382-1410)
- H.S. Roelfsema
Institutions
- Leiden University Medical Center (NL)
- Dimence (NL)
- GGz centraal (NL)
- St. Antonius Ziekenhuis (NL)
- Flevoziekenhuis (NL)
- GGZ inGeest (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Haifa (IL)
Publication Details
- Journal
- American Journal of Geriatric Psychiatry
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jagp.2025.12.002
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00