Combined association of triglyceride-glucose index and the atherogenic index of plasma with the incidence of cardiovascular diseases among middle-aged and older population
Both baseline and longitudinal changes of TyG-AIP were independently associated with the risk of developing CVDs, especially stroke, in middle-aged and older Chinese adults. Repeated assessment of TyG-AIP captured cardiometabolic deterioration over time and improved identification of individuals at elevated cardiovascular risk. Incorporating long-term monitoring of TyG-AIP into routine health evaluations may enhance population-level CVDs risk prediction and support more effective prevention strategies.
Authors
- Haicheng Fei (ORCID: https://orcid.org/0009-0006-9175-663X)
- Xueyu Chen (ORCID: https://orcid.org/0000-0002-7066-0501)
- Wenjuan Wang (ORCID: https://orcid.org/0000-0001-9884-4217)
- Yixin Zhang (ORCID: https://orcid.org/0000-0002-1146-8122)
- Zhang Liu (ORCID: https://orcid.org/0000-0001-8433-6289)
- Xu Cuiping (ORCID: https://orcid.org/0000-0002-8868-4878)
- Xuezhen Zhao
- Jinhong Pang
- Jianhong Qiao
Institutions
- Shandong University of Aeronautics (CN)
- Shandong University (CN)
- Binzhou People's Hospital (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong First Medical University (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-12-14
- DOI
- https://doi.org/10.1186/s12933-025-03038-3
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00