Incidence of pyloric gland adenoma located within the gallbladder

Pyloric gland adenoma (PGA) of the gallbladder is a rare benign epithelial tumor with potential for malignant transformation. PGAs represent the most common histologic subtype of gallbladder adenomas and are frequently associated with chronic inflammation. Although often incidental findings, their malignant potential warrants careful histopathologic evaluation and consideration for surveillance or surgical management. We present the case of a 64-year-old man with a 30-year history of episodic epigastric pain radiating to the right abdomen and back. Abdominal ultrasound revealed a stalked lesion communicating with the gallbladder, confirmed as a PGA on final pathology after robotic-assisted laparoscopic cholecystectomy.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-11-23
DOI
https://doi.org/10.1093/jscr/rjaf976
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Incidence of pyloric gland adenoma located within the gallbladder

So Un Kim, Aldin Malkoc, Sharmila Raju, Gladys Vargas et al.
Journal of Surgical Case Reports
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Incidence of pyloric gland adenoma located within the gallbladder

So Un Kim, Aldin Malkoc, Sharmila Raju, Gladys Vargas, Brandon Woodward, Harpreet Gill, Mostafa Mohammed, Neda Salami, Ahmad Ibrahim, Sean Hormozian
article en

Abstract

Pyloric gland adenoma (PGA) of the gallbladder is a rare benign epithelial tumor with potential for malignant transformation. PGAs represent the most common histologic subtype of gallbladder adenomas and are frequently associated with chronic inflammation. Although often incidental findings, their malignant potential warrants careful histopathologic evaluation and consideration for surveillance or surgical management. We present the case of a 64-year-old man with a 30-year history of episodic epigastric pain radiating to the right abdomen and back. Abdominal ultrasound revealed a stalked lesion communicating with the gallbladder, confirmed as a PGA on final pathology after robotic-assisted laparoscopic cholecystectomy.

Journal of Surgical Case ReportsVol. 2025(12)
Arrowhead Regional Medical Center (US)
Openalex Percentile: Top 40%
Cholangiocarcinoma and Gallbladder Cancer Studies
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