Co-delivery of camptothecin and SH3RF3-AS1 SiRNA for glioma synergistic therapy
Our findings provide valuable insights into the roles of m6A demethylation-mediated upregulation of SH3RF3-AS1 in supporting glioma proliferation and demonstrate the potential of Nano<sup>PCPT</sup>/siRNA@U251 as an innovative chemotherapeutic strategy for glioma.
Authors
- Jing Zou (ORCID: https://orcid.org/0000-0002-3618-9672)
- Zhiyue Zhang (ORCID: https://orcid.org/0000-0001-7070-2532)
- Jun Jiang (ORCID: https://orcid.org/0000-0002-6342-165X)
- Chuncheng Qu
- Shun Wang (ORCID: https://orcid.org/0000-0001-7907-7112)
- Lei Liang (ORCID: https://orcid.org/0000-0001-5421-9380)
- Chéng Wáng (ORCID: https://orcid.org/0000-0002-0178-8317)
- Donghai Wang (ORCID: https://orcid.org/0000-0003-4273-6115)
- Z W Nie
Institutions
- Qilu University of Technology (CN)
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-12-14
- DOI
- https://doi.org/10.1186/s12935-025-04119-9
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00