Fetal biochemistry in CAKUT: Insights from 40 Years of reference center experience
Despite the invasiveness of fetal sampling and the need for specialized expertise, biochemical markers provide crucial insights for prenatal counseling and individualized management in CAKUT. Future research should focus on non-invasive alternatives, such as amniotic fluid proteomics and urinary biomarkers, to refine risk assessment and improve neonatal outcomes. Standardizing protocols and integrating biochemical testing into routine prenatal care could significantly enhance the early detection and management of CAKUT.
Authors
- Liza Ali
- Alaa El‐Ghoneimi (ORCID: https://orcid.org/0000-0001-8133-2979)
- V. Bidault (ORCID: https://orcid.org/0000-0002-2163-8455)
- Matthieu Peycelon (ORCID: https://orcid.org/0000-0003-3617-4849)
- Irene Paraboschi (ORCID: https://orcid.org/0000-0003-3529-1437)
- Etienne Voirin‐Mathieu
- Ugo Maria Pierucci (ORCID: https://orcid.org/0000-0001-7370-5122)
- Jonathan Rosenblatt (ORCID: https://orcid.org/0000-0001-8877-0381)
- A.-A. Lachkar
- Françoise Müller (ORCID: https://orcid.org/0000-0003-3853-7412)
- Sophie Dreux
- A. Paye Jaouen
- Florence JULIEN MARSOLIER
Institutions
- European Organisation for Rare Diseases (FR)
- Inserm (FR)
- University of Milan (IT)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Université Sorbonne Paris Nord (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Hôpital Robert-Debré (FR)
- Ospedale dei Bambini Vittore Buzzi (IT)
Publication Details
- Journal
- Journal of Pediatric Urology
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1016/j.jpurol.2025.12.008
- Primary Topic
- Pediatric Urology and Nephrology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00