Inhibition of the Mevalonate Pathway Targets Neuroblastoma Stem Cells

Treatment with mevalonate pathway inhibitors leads to reduced neuroblastoma cancer stem cell function through reductions in protein geranylgeranylation.

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Publication Details

Journal
Pharmacology
Published
2025-12-13
DOI
https://doi.org/10.1159/000549949
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Inhibition of the Mevalonate Pathway Targets Neuroblastoma Stem Cells

Jeffrey D. Neighbors, Michelle V. Green, J. Reed, Christina E. Zielinski
Pharmacology
Cancer, Lipids, and Metabolism
article

Inhibition of the Mevalonate Pathway Targets Neuroblastoma Stem Cells

Jeffrey D. Neighbors, Michelle V. Green, J. Reed, Christina E. Zielinski
article en

Abstract

Treatment with mevalonate pathway inhibitors leads to reduced neuroblastoma cancer stem cell function through reductions in protein geranylgeranylation.

PharmacologyVol. 111(1)
Penn State Milton S. Hershey Medical Center (US), Texas A&M University (US)
Openalex Percentile: Top 51%
Cancer, Lipids, and Metabolism
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Inhibition of the Mevalonate Pathway Targets Neuroblastoma Stem Cells — Jeffrey D. Neighbors, Michelle V. Green, et al. · Pharmacology (2025) | TGRS Research Map | TGRS