Using Raman spectroscopy to analyse in situ a precipitate appearing in a catheter line after drug co-administration

Raman spectroscopy in combination with a database was used for rapid and non-invasive bulk identification in situ. However, to confirm or refute small amounts of a second drug substance in the precipitate, a large area scan of the particle on a flat surface is recommended.

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Publication Details

Journal
European Journal of Hospital Pharmacy
Published
2025-12-13
DOI
https://doi.org/10.1136/ejhpharm-2025-004664
Primary Topic
Spectroscopy Techniques in Biomedical and Chemical Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Using Raman spectroscopy to analyse in situ a precipitate appearing in a catheter line after drug co-administration

Ingunn Tho, Niklas Nilsson, Ellen Hagesæther, Kaveh Teimori et al.
European Journal of Hospital Pharmacy
Spectroscopy Techniques in Biomedical and Chemical Research
article

Using Raman spectroscopy to analyse in situ a precipitate appearing in a catheter line after drug co-administration

Ingunn Tho, Niklas Nilsson, Ellen Hagesæther, Kaveh Teimori, Ingeborg Karboe
article en

Abstract

Raman spectroscopy in combination with a database was used for rapid and non-invasive bulk identification in situ. However, to confirm or refute small amounts of a second drug substance in the precipitate, a large area scan of the particle on a flat surface is recommended.

European Journal of Hospital Pharmacy
University of Oslo (NO)
Openalex Percentile: Top 73%
Spectroscopy Techniques in Biomedical and Chemical Research
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