Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury
rTMS is associated with improvements in motor function and anti-apoptotic molecular changes in SCI rats, possibly via modulation of MAPK and PI3K/AKT signaling pathways, including upregulation of Bcl-2 and downregulation of Bax and caspase-3.
Authors
- Hemu Chen (ORCID: https://orcid.org/0000-0001-5729-6453)
- Jin-xiu Liu
- Juan Song (ORCID: https://orcid.org/0000-0002-2104-1763)
- Qingqin Xu (ORCID: https://orcid.org/0000-0003-3844-5139)
- Jianwei Lü (ORCID: https://orcid.org/0000-0003-4183-4303)
- Junhua Wang (ORCID: https://orcid.org/0000-0002-6110-3711)
- Mengyu Yang (ORCID: https://orcid.org/0009-0005-3302-7095)
- Lei Qian (ORCID: https://orcid.org/0000-0002-3480-4248)
- Junhong Su (ORCID: https://orcid.org/0009-0008-5409-0394)
Institutions
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111687
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00