Impact of Sinus Surgery on Bacteriome Composition in Patients With Chronic Rhinosinusitis With Nasal Polyps
Staphylococcus aureus showed a significant increase in relative abundance in CRSwNP patients following endoscopic sinus surgery compared to pre-surgery samples. Other Staphylococcus species were found to correlate positively with S. aureus in patients with nasal polyps; among those, S. caprae correlated strongly while being the most represented in samples. Patients with recurrent nasal polyp growth exhibited a substantially greater postoperative increase in the relative abundance of S. aureus.
Authors
- Esha Sehanobish (ORCID: https://orcid.org/0000-0003-1090-2991)
- Patrick M. Colley (ORCID: https://orcid.org/0009-0007-8304-7339)
- Casper H.Y. Chung
- M. A. Vorobjeva (ORCID: https://orcid.org/0000-0002-6579-6869)
- Jovanka M. Voyich (ORCID: https://orcid.org/0009-0004-0200-7123)
- Erin K. O’Brien (ORCID: https://orcid.org/0000-0002-4891-9548)
- Hirohito Kita (ORCID: https://orcid.org/0000-0002-6854-2936)
- Kathryn A. Knoop (ORCID: https://orcid.org/0000-0003-2007-3066)
- C.‐C. Chen (ORCID: https://orcid.org/0000-0003-2581-1830)
- Masaki Orihara (ORCID: https://orcid.org/0000-0002-8182-9800)
- Elina Jerschow (ORCID: https://orcid.org/0000-0002-9066-2483)
- Connie B. Chang (ORCID: https://orcid.org/0000-0001-9555-8223)
- Aleksandr iAkushev (ORCID: https://orcid.org/0009-0001-7040-7792)
- Ann Scott (ORCID: https://orcid.org/0009-0000-5492-8937)
- Nadeem A. Akbar (ORCID: https://orcid.org/0000-0001-6108-6985)
Institutions
- Albert Einstein College of Medicine (US)
- Mayo Clinic (US)
- Montana State University (US)
- WinnMed (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- International Forum of Allergy & Rhinology
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1002/alr.70082
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00