Physical performance outweighs grip strength in predicting diabetes risk: evidence from a prospective cohort study
Physical performance surpasses grip strength as a predictor of new-onset diabetes, particularly in middle-aged and non-obese individuals. As a brief, low-resource assessment of lower-limb performance, it provides a practical and scalable tool for identifying high-risk individuals, especially young lean adults who are often missed by traditional risk models.
Authors
- Qin Zhu (ORCID: https://orcid.org/0000-0001-5539-6071)
- Hongxia Liu (ORCID: https://orcid.org/0000-0002-0170-4048)
- Ning Chen (ORCID: https://orcid.org/0000-0001-6806-4287)
- Ting Zhang (ORCID: https://orcid.org/0000-0002-5748-9754)
- Rui Du (ORCID: https://orcid.org/0000-0003-3736-7909)
- T. T. Han (ORCID: https://orcid.org/0000-0001-6487-0281)
- Yurong Weng
- Ping Hu (ORCID: https://orcid.org/0009-0008-1506-7319)
- Ting Liu (ORCID: https://orcid.org/0000-0003-0669-996X)
- Mingyu Zhu
- Rong Huang (ORCID: https://orcid.org/0000-0003-2570-9748)
- Mi Xiang (ORCID: https://orcid.org/0000-0002-1944-2920)
- Yuru Yan
- Jie Cao (ORCID: https://orcid.org/0000-0003-1555-7795)
- Yaomin Hu
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Guangzhou Experimental Station (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1186/s12967-025-07473-4
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00