Multimorbidity and risk of atrial fibrillation in the Lifelines cohort
There was a dose-dependent relationship between the number of total comorbidities and cardiovascular comorbidities and risk of incident AF, but not for non-cardiovascular comorbidities. We identified 12 comorbidity clusters with different risks of incident AF; however, these clusters were determined by the number of comorbidities rather than specific combinations.
Authors
- Isabelle C. Van Gelder (ORCID: https://orcid.org/0000-0002-7579-1201)
- Colinda van Deutekom (ORCID: https://orcid.org/0000-0001-5116-7378)
- Barbara C. Van Munster (ORCID: https://orcid.org/0000-0001-6056-7795)
- Marieke J H Velt (ORCID: https://orcid.org/0000-0002-2492-844X)
- Liann I. Weil (ORCID: https://orcid.org/0000-0002-3505-7416)
- Michelle Samuel (ORCID: https://orcid.org/0000-0002-9674-6565)
- Michiel Rienstra (ORCID: https://orcid.org/0000-0002-2581-070X)
- Victor W Zwartkruis (ORCID: https://orcid.org/0000-0003-0115-1313)
- Richard C. Oude Voshaar (ORCID: https://orcid.org/0000-0003-1501-4774)
- Melissa E. Middeldorp (ORCID: https://orcid.org/0000-0002-4106-9771)
- Bastiaan Geelhoed
- Denise Hanssen (ORCID: https://orcid.org/0000-0003-0119-9608)
Institutions
- Dalhousie University (CA)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1093/ehjopen/oeaf164
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Ministerie van Volksgezondheid, Welzijn en Sport
- Universitair Medisch Centrum Groningen