Fucoidan potentiates anti-tumor efficacy of CAR-T cells against non-Hodgkin lymphoma by activation of STAT3 pathway
These findings elucidate the supportive role of FO in enhancing CAR-T cell function, which indicates FO's clinical potential as immunomodulatory supplement to potentiate CAR-T therapy against NHL.
Authors
- Xuanren Shi (ORCID: https://orcid.org/0000-0002-1786-6121)
- Liang Zhang (ORCID: https://orcid.org/0000-0001-7082-8258)
- Xiaoqing Wu (ORCID: https://orcid.org/0000-0003-2076-4107)
- Qingzheng Kang
Institutions
- Sun Yat-sen University (CN)
- Shenzhen University (CN)
- University of Hong Kong - Shenzhen Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
- Wuhan Sports University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1186/s12967-025-07548-2
- Primary Topic
- Seaweed-derived Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00