Atypical Oral Presentation of Giant Cell Arteritis With Subsequent Middle Cerebral Artery Involvement

Giant cell arteritis (GCA) is a large-vessel vasculitis classically affecting the temporal arteries and associated with visual loss and constitutional symptoms. We report a rare and diagnostically challenging case of GCA in an elderly patient presenting with progressive visual impairment, anterior circulation stroke, vasculitic mouth ulcer, and dysphagia requiring nasogastric feeding. Diagnosis was confirmed by ultrasound findings without histological confirmation. This case underlines the potential for GCA to present with multisystem ischemic manifestations and the importance of early recognition and corticosteroid therapy.

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Publication Details

Journal
Cureus
Published
2025-12-13
DOI
https://doi.org/10.7759/cureus.99107
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Atypical Oral Presentation of Giant Cell Arteritis With Subsequent Middle Cerebral Artery Involvement

Christopher G. Mathew, Alamin Alkundi
Cureus
Vasculitis and related conditions
article

Atypical Oral Presentation of Giant Cell Arteritis With Subsequent Middle Cerebral Artery Involvement

Christopher G. Mathew, Alamin Alkundi
article en

Abstract

Giant cell arteritis (GCA) is a large-vessel vasculitis classically affecting the temporal arteries and associated with visual loss and constitutional symptoms. We report a rare and diagnostically challenging case of GCA in an elderly patient presenting with progressive visual impairment, anterior circulation stroke, vasculitic mouth ulcer, and dysphagia requiring nasogastric feeding. Diagnosis was confirmed by ultrasound findings without histological confirmation. This case underlines the potential for GCA to present with multisystem ischemic manifestations and the importance of early recognition and corticosteroid therapy.

CureusVol. 17(12)
University of Liverpool (GB), Medway School of Pharmacy (GB), North Devon District Hospital (GB), Royal Liverpool University Hospital (GB)
Openalex Percentile: Top 41%
Vasculitis and related conditions
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