Pro-inflammatory cytokines in response to systemic inflammatory response syndrome post extra-corporeal membrane oxygenator decannulation
In patients developing SIRS following VA-ECMO decannulation, plasma levels of key pro-inflammatory cytokines remained largely unchanged over a 24-h period. These findings suggest that the clinical manifestations of SIRS in this context may not be directly driven by traditional pro-inflammatory cytokine surges, warranting further investigation into alternative inflammatory mediators or mechanisms.Registered in clinical trials registry:NCT04678518, MRC-01-20-155.
Authors
- Cornelia S Carr (ORCID: https://orcid.org/0000-0002-0247-220X)
- Shahab Uddin (ORCID: https://orcid.org/0000-0003-1886-6710)
- Amr Salah Omar (ORCID: https://orcid.org/0000-0001-8560-2745)
- A. A. K. Salama (ORCID: https://orcid.org/0000-0003-2065-9702)
- Rasha Kaddoura (ORCID: https://orcid.org/0000-0003-2613-9759)
- Ousama Bilal
- Rula Taha
- Abdulaziz Alkhulaifi (ORCID: https://orcid.org/0000-0002-3521-1364)
- Laith Tbishat (ORCID: https://orcid.org/0000-0002-9611-5712)
- Kirti S. Prabhu
- Abdulrasheed Pattath
Institutions
- Beni-Suef University (EG)
- Al-Azhar University (EG)
- Weill Cornell Medical College in Qatar (QA)
- Hamad Medical Corporation (QA)
- Qatar University (QA)
Publication Details
- Journal
- The International Journal of Artificial Organs
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1177/03913988251398846
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00