Association of systemic corticosteroids and clinical outcomes in children hospitalised with severe orbital infections
In a large cohort of hospitalised children with severe orbital infections, corticosteroids were used infrequently, and when used, were not associated with improved clinical outcomes. Further high-quality trial evidence is needed to determine if routine corticosteroids are safe and effective.
Authors
- Gita Wahi (ORCID: https://orcid.org/0000-0001-5943-9702)
- Jessica L. Foulds (ORCID: https://orcid.org/0000-0002-2471-0432)
- Ronik Kanani
- Eleanor Pullenayegum (ORCID: https://orcid.org/0000-0003-4265-1330)
- Patricia C. Parkin (ORCID: https://orcid.org/0000-0003-2935-7145)
- Mahmoud Sakran
- Olivier Drouin (ORCID: https://orcid.org/0000-0003-1429-9341)
- Catherine Pound (ORCID: https://orcid.org/0000-0003-2004-7749)
- Clarelle L. Gonsalves (ORCID: https://orcid.org/0000-0002-4758-8337)
- Peter J. Gill (ORCID: https://orcid.org/0000-0002-6253-1312)
- Gemma Vomiero
- Arun Reginald
- Elysa Widjaja (ORCID: https://orcid.org/0000-0003-0986-5476)
- Cornelia M. Borkhoff (ORCID: https://orcid.org/0000-0003-3420-1866)
- Sanjay Mahant (ORCID: https://orcid.org/0000-0003-0487-5835)
- Nikolaus E. Wolter (ORCID: https://orcid.org/0000-0002-5196-6150)
- Ann Bayliss
- Julie Quet
- Anupam Sehgal
Institutions
- University of Ottawa (CA)
- University of Toronto (CA)
- Children's Hospital of Eastern Ontario (CA)
- Lakeridge Health (CA)
- North York General Hospital (CA)
- Trillium Health Centre (CA)
- Hospital for Sick Children (CA)
- Alberta Children's Hospital (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Public Health Ontario (CA)
- SickKids Foundation (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Kingston Health Sciences Centre (CA)
- Stollery Children's Hospital (CA)
- McMaster University (CA)
Publication Details
- Journal
- BMJ Paediatrics Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjpo-2025-004161
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00