Efficacy and safety of dapsone in adult immune thrombocytopenia: a systematic review and meta-analysis
Dapsone demonstrates moderate efficacy and an acceptable safety profile in adult ITP patients, especially in resource-limited contexts. While it may not match thrombopoietin agonists in preventing relapse, its low cost and oral administration offer practical advantages. Further large-scale randomized trials are warranted to clarify its role in ITP management.
Authors
- Shafiq ur Rehman (ORCID: https://orcid.org/0000-0002-1265-3442)
- Iftikhar Khan (ORCID: https://orcid.org/0009-0004-9579-011X)
- Ahmad Omar Saleh (ORCID: https://orcid.org/0009-0005-5947-0511)
- Samia Aleem (ORCID: https://orcid.org/0000-0003-0291-7608)
- Haris Mumtaz Malik (ORCID: https://orcid.org/0009-0007-4657-9723)
- Hammad Javaid (ORCID: https://orcid.org/0009-0002-8938-0435)
- Syed Ahtisham Halim
- Soban Ali Qasim
- Shree Rath (ORCID: https://orcid.org/0009-0000-4273-0827)
- Kamil Ahmad Kamil (ORCID: https://orcid.org/0009-0000-8208-0689)
Institutions
- University of Jordan (JO)
- King Edward Medical University (PK)
- Khyber Medical College (PK)
- Rawalpindi Medical University (PK)
- Nishtar Medical College and Hospital (PK)
- CMH Lahore Medical College and Institute of Dentistry (PK)
- Jinnah Sindh Medical University (PK)
- Kandahar University (AF)
- University of Management and Technology (PK)
- All India Institute of Medical Sciences Bhubaneswar (IN)
- Khyber Girls Medical College
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1186/s40001-025-03427-0
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00