Longitudinal analysis of gut microbiota dysbiosis and bacterial signatures predictive of postoperative enterocolitis in children with Hirschsprung disease
Patients with HSCR exhibited distinct alterations in the gut microbiota, with significant shifts observed between the pretreatment period and 6 months postoperatively. Specific bacterial taxa were identified as potential markers for HAEC development. Future microbiome-targeted interventions to prevent HAEC need to be explored.
Authors
- Nipon Chattipakorn (ORCID: https://orcid.org/0000-0003-3026-718X)
- Sireekarn Chantakhow
- Kanokkan Tepmalai (ORCID: https://orcid.org/0000-0003-2298-9385)
- Jiraporn Khorana (ORCID: https://orcid.org/0000-0001-9023-0923)
- Chanon Kunasol (ORCID: https://orcid.org/0000-0003-1744-0005)
Institutions
- The Royal College Of Anesthesiologists Of Thailand (TH)
- Office of the Royal Society
- Chiang Mai University (TH)
Publication Details
- Journal
- Clinical and Experimental Pediatrics
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3345/cep.2025.01886
- Primary Topic
- Congenital gastrointestinal and neural anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Council of Thailand