Hepatic steatosis detected on low‐dose computed tomography in high‐risk participants of a lung cancer screening programme: a retrospective observational study
Moderate to severe hepatic steatosis was detected on low-dose computed tomography (LDCT) in 15% of participants undergoing lung cancer screening in a retrospective observational study. Almost half of participants with hepatic steatosis (21/45) were at intermediate risk of liver fibrosis, with four participants (8.9%) at high risk based on Fibrosis-4 scores. Based on current guidelines, these participants would be recommended to undergo further evaluation for liver disease. The clinical impact of moderate to severe hepatic steatosis incidentally detected on lung cancer screening LDCT requires further consideration and evaluation.
Authors
- Stephen Lam (ORCID: https://orcid.org/0000-0002-3964-1492)
- Emily C.A. Stone (ORCID: https://orcid.org/0000-0001-9021-8449)
- Michelle Chua (ORCID: https://orcid.org/0000-0002-3135-6478)
- Annette M. McWilliams (ORCID: https://orcid.org/0000-0002-3799-8527)
- Henry Marshall (ORCID: https://orcid.org/0000-0002-9626-8014)
- Diane Pascoe
- Renée Manser
- Siddharth Sood (ORCID: https://orcid.org/0000-0002-9341-4792)
- Fraser Brims (ORCID: https://orcid.org/0000-0002-6725-7535)
- Asha Bonney (ORCID: https://orcid.org/0000-0003-3647-3902)
- Daniel Steinfort (ORCID: https://orcid.org/0000-0002-8998-2949)
- Kwun M. Fong (ORCID: https://orcid.org/0000-0002-6507-1403)
- Mark McCusker (ORCID: https://orcid.org/0009-0003-7009-9288)
- Paul Fogarty
Institutions
- The Royal Melbourne Hospital (AU)
- University of British Columbia (CA)
- The University of Melbourne (AU)
- Northern Health (AU)
- Curtin University (AU)
- Epworth Hospital (AU)
- Fiona Stanley Hospital (AU)
- Sir Charles Gairdner Hospital (AU)
- St Vincent's Clinic (AU)
- Prince Charles Hospital (AU)
- Institute for Respiratory Health (AU)
Publication Details
- Journal
- Internal Medicine Journal
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1111/imj.70263
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00