Cognitive profiles at presentation and subsequent cognitive decline and quality of life in Parkinson's disease
Data-driven approach to identify cognitive profiles. Cognitive decline across domains assessed by risk of reliable cognitive change. Cognitive profiles did not predict rate of cognitive decline. Memory impairment profile had a higher risk of reliable cognitive change.
Authors
- Anthony E. Lang (ORCID: https://orcid.org/0000-0003-1229-3667)
- David P. Breen (ORCID: https://orcid.org/0000-0001-9643-3713)
- Paula McLaughlin (ORCID: https://orcid.org/0000-0001-7173-8449)
- Saira Saeed Mirza (ORCID: https://orcid.org/0000-0002-0973-2246)
- Susan Helen Fox (ORCID: https://orcid.org/0009-0004-7568-1645)
- Brian Levine (ORCID: https://orcid.org/0000-0003-4343-811X)
- David A. Grimes (ORCID: https://orcid.org/0000-0002-2115-1866)
- Keera N. Fishman (ORCID: https://orcid.org/0000-0002-9573-0369)
- Malcolm A. Binns (ORCID: https://orcid.org/0000-0001-9998-6612)
- Sarah Duff‐Canning
- Connie Marras
- Mario Masellis
- Mark Mapstone
- Sandra E. Black
- Angela K. Troyer
Institutions
- Dalhousie University (CA)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- University of Ottawa (CA)
- University of Toronto (CA)
- University of California, Irvine (US)
- Toronto Western Hospital (CA)
- Ontario Shores Centre for Mental Health Sciences (CA)
- Health Sciences Centre (CA)
- Baycrest Hospital (CA)
- Health Sciences North (CA)
- MRC Centre for Regenerative Medicine (GB)
- Ontario Brain Institute (CA)
- Krembil Research Institute
- University of Edinburgh (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz.70912
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondation Brain Canada
- Canadian Institutes of Health Research