Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank

In the normoglycemia subgroup, the association between the TyG-ABSI and ASCVD was nonlinear. Moreover, the TyG-ABSI was linearly associated with an increased risk of ASCVD in the diabetes subgroup but not in the dysglycemia subgroup. The predictive value of the TyG-ABSI across different glycemic statuses provides new evidence for medical practice. Furthermore, the TyG-ABSI may serve as a useful tool for identifying high-risk individuals within the seemingly low-risk normoglycemic population and for further risk identification among diabetic patients.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2025-12-13
DOI
https://doi.org/10.1186/s12933-025-03021-y
Citations
3
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
3.88
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article

Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank

Zhixin Tan, Aijun Chen, Jin Chen, Jingbo Zhang et al.
3 citations
Cardiovascular Diabetology
Diabetes, Cardiovascular Risks, and Lipoproteins
3.88
article

Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank

Zhixin Tan, Aijun Chen, Jin Chen, Jingbo Zhang, Lifu Sun, Xinyi Shao, Yidian Fu, Genlong Bai
article en
3 citations

Abstract

In the normoglycemia subgroup, the association between the TyG-ABSI and ASCVD was nonlinear. Moreover, the TyG-ABSI was linearly associated with an increased risk of ASCVD in the diabetes subgroup but not in the dysglycemia subgroup. The predictive value of the TyG-ABSI across different glycemic statuses provides new evidence for medical practice. Furthermore, the TyG-ABSI may serve as a useful tool for identifying high-risk individuals within the seemingly low-risk normoglycemic population and for further risk identification among diabetic patients.

Cardiovascular DiabetologyVol. 24(1)
Hebei General Hospital (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN), The University of Osaka (JP)
Openalex Percentile: Top 6%
Diabetes, Cardiovascular Risks, and Lipoproteins
3.88
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